3D bioprinting ipuratifomu yepamusoro yekugadzira iyo inogona kushandiswa kudhinda matishu kubva kumaseru uye pakupedzisira yakakosha nhengo. Izvi zvinogona kuvhura nyika nyowani mukurapa uku zvichibatsira zvakananga varwere vanoda kutsiva nhengo.
Panzvimbo pekumirira mupi akakodzera kana kuisa mungozi muviri uchiramba mutezo wakasimwa, varwere vane mutezo wetsika wakavakirwa nechinangwa kutsiva wakaremara. Nekudaro, kunyangwe nekufambira mberi kwe3D bioprinting mumakore makumi maviri apfuura, ichiri kushaya kufambira mberi kwakakosha kuitira kugadzira yakaoma 3D biomimetic tishu inovaka.
Sekureva kwevatsvagiri vekuSingapore University yeTekinoroji uye Dhizaini (SUTD), Nanyang Technological University (NTU) neAsia University, matekinoroji etsika kunyanya anoda kukurumidzirwa kugadzirisa bhodhoro mukukura bioprinted multicellular 3D tishu inovaka kuita matishu anoshanda. Pepa ravo rekutsvagisa, rine musoro unoti “Ndidhindire organ! Sei tisati tasvika?” rakabudiswa muAdvances muPolymer Science.
Mune pepa iri, vatsvakurudzi vanopawo kuongorora kwakadzama kwekuvandudzwa kwemazuva ano uye kuongorora teknolojia yezvinyorwa zvebioprinting.Kufambira mberi mukugadzirwa kwebioink, kushandiswa kwezvitsva zvebioprinting uye matutuation maturation mazano anoongororwawo. Kunyanya kutariswa kunopihwawo kune basa repolymer sainzi uye kuti inozadzisa sei 3D bioprinting kukunda zvimwe zvipingaidzo zvakakura mumunda wekudhinda nhengo, sekugonesa biomimetic, angiogenesis uye 3D anatomy-inoenderana nebiological zvimiro (sezvinoratidzwa pazasi mifananidzo).
Kushandiswa kwemaitiro ekuwedzera, akadai seakasimba co-tsika perfusion masisitimu, anoonekwa seakakosha kuve nechokwadi chekukura uye kusangana kwebioprinted tishu inovaka. Kunyangwe iko zvino zvave kugona kugadzira matishu emunhu kana nhengo dzinogona kukura kuita vascularized uye inoshanda zvishoma, indasitiri ichiri kusarira kumashure mu bioprinting yeanhu-akanangana nematishu kana nhengo nekuda kwekuomarara kwetishu-chaiyo extracellular matrix (ECM) uye maturation process - kushaikwa kwakakodzera co-tsika yezvenhau kuti itsigire akawanda maseru mamiriro.
"Kunyange zvazvo 3D bioprinting ichiri mumatanho ekutanga, kusvetuka kunoshamisa kwayakaita mumakore achangopfuura kunoratidza chokwadi chekupedzisira chenhengo dzakakura dzakakura." Zvisineyi, kuti tisundire miganhu yemishonga, tinofanira kukunda matambudziko ehunyanzvi ekugadzira matishu. Mabioinks chaiwo haagadzirise maitiro ekukura kwetishu. Izvi zvinozopedzisira zvave neruremekedzo rukuru kune hupenyu hwevarwere ve3D," akadaro Purofesa we3D. Chua Chee Kai, munyori anotungamira webepa.
JS Additive's 3D yekudhinda sevhisi yanga ichienderera mberi nekuvandudza uye kufambira mberi, iyo inosvika padanho repamusoro muindasitiri yekurapa kuzadzisa zvinodiwa nevarwere vakuru uye netsvagiridzo yesainzi. Yedu 3D yakadhindwa mhando dzekurapa uye zvigadzirwa zvakapedzwa zvinoshandiswa zvakanyanya mukushandisa mhiri kwemakungwa. Kugamuchirwa uye kushandisa.
